Study #13 · Chapter B

    Myeloperoxidase and natural defense against bacteria

    Original title: Myeloperoxidase: friend and foe.

    Authors
    Seymour J. Klebanoff
    Journal
    Journal of Leukocyte Biology
    Year
    2005

    Summary

    This review discusses myeloperoxidase, an enzyme used by immune cells to tackle microorganisms. Through myeloperoxidase, substances like HOCl can be formed, which can damage bacteria and other invaders. Simultaneously, overactivity can contribute to inflammatory damage. The publication shows how powerful, yet sensitive to balance, this part of the immune system is.

    What was investigated

    This review discusses myeloperoxidase, an enzyme immune cells use against pathogens.

    What were the findings

    The review describes myeloperoxidase as an important defense enzyme. It helps immune cells fight bacteria and other invaders via substances such as HOCl. At the same time, overactivity of this system can contribute to inflammatory damage.

    Why relevant for halotherapy

    Immune cells use myeloperoxidase to create powerful substances against bacteria and other pathogens. One of those substances is HOCl. Since HOCl arises from chloride, this article establishes a direct biological link between salt, chloride, and natural defense. For halotherapy, this is important: dry salt particles contain chloride and can thus be positioned within the broader defense system of the airways.

    Original publication

    Seymour J. Klebanoff. Myeloperoxidase: friend and foe. Journal of Leukocyte Biology, 2005.

    pubmed.ncbi.nlm.nih.gov/15689384/
    myeloperoxidaseMPObacteriënHOClafweercellennatuurlijke afweer

    This summary has been prepared for readability and does not replace the original scientific publication. Consult the source via the link for the full context. Halotherapy is a complementary approach to promoting health and does not replace medical treatment or advice from your treating physician.

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