Study #37 · Chapter E
Safety of inhaled hypertonic saline solution in asthma
Original title: Safety and benefits of inhaled hypertonic saline following airway challenges with endotoxin and allergen in asthmatics.
- Authors
- Neil E. Alexis, William Bennett, David Blaine Peden
- Journal
- Journal of Asthma
- Year
- 2017
Summary
Researchers investigated the safety and tolerability of inhaled hypertonic saline in people with mild to moderate asthma. Participants were exposed to airway triggers such as endotoxin and house dust mite allergen. It was then examined how the airways responded to hypertonic salt inhalation. In this small controlled setting, hypertonic saline was well tolerated without clear safety issues.
What was investigated
Researchers investigated whether inhaling hypertonic saline solution was safe and tolerable in people with mild to moderate asthma. Participants were exposed to airway triggers such as endotoxin and house dust mite allergen. It was then observed how the airways reacted to hypertonic salt inhalation.
What were the findings
The study shows that inhaled hypertonic saline was safely tolerated in this small group of people with mild to moderate asthma, both before and within 24 hours after exposure to airway triggers such as endotoxin and house dust mite allergen. The main outcome is thus primarily safety and tolerability: the treatment could be applied in this controlled scientific setting without clear safety problems.
Why relevant for halotherapy
Halotherapy brings salt into contact with sensitive airways. This research is therefore important for the safety aspect: it shows that hypertonic salt inhalation can be well tolerated in mild to moderate asthma under controlled conditions.
Original publication
Neil E. Alexis, William Bennett, David Blaine Peden. Safety and benefits of inhaled hypertonic saline following airway challenges with endotoxin and allergen in asthmatics. Journal of Asthma, 2017.
pubmed.ncbi.nlm.nih.gov/28095128/This summary has been prepared for readability and does not replace the original scientific publication. Consult the source via the link for the full context. Halotherapy is a complementary approach to promoting health and does not replace medical treatment or advice from your treating physician.